A targeting vector was designed to insert a single loxP site upstream of exon 2, and an FRT-flanked neomycin resistance (neo) cassette, followed by a second loxP site, downstream of exon 2 of the gene. Recombinase mediated recombination removed the FRT-flanked neo cassette and exon 2. (J:236306)
Basic Information
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count