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EN
Mice bearing this transgene express truncated mouse Rem1 cDNA (rad and gem related GTP binding protein 1; an L-type Ca2+ channel (LTCC) inhibitor) cDNA corresponding to amino acids 1-265 fused at its amino terminal to the canonical caveolin binding domain (CBD; RNVPPIFNDVYWIAF) under the conditional control of the mouse Myh6 (myosin, heavy polypeptide 6, cardiac muscle, alpha) promoter and the tetracycline-responsive element (TRE or tetO). Carboxy-terminal truncation of the REM protein inhibits membrane association. (J:101977)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
