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A loxP site and FRT flanked neomycin selection cassette were inserted in intron 9a and a second loxP site was inserted in exon 13 in the 3' untranslated region. The selection cassette was subsequently removed from the properly targeted allele using flp recombinase, and exons 10 through the coding part of exon 13 were removed via Cre-mediated recombination in the germline. (J:227336)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
