A neomycin resistance cassette flanked by both FRT and loxP sites was inserted upstream of exon 4 and a third loxP site downstream of exon 5. The neo cassette was excised in the germline by flp recombinase. (J:240861)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count