A targeting vector was designed to insert a loxP sequence and a neo cassette into the region between exons 4 and 5, and a loxP sequence between exons 6 and 7 of the gene. Subsequent cre-mediated recombination to remove the neo cassette resulted in exons 5 and 6 flanked by loxP sites. (J:236234)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
Insertion
--
1
2
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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