Exons 4 through 6 flanked by loxP sites, which by itself causes aberrant mRNA splicing and reduction of wild-type protein. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette. (J:248771)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count