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The transgenic construct contains a mutated rat transforming growth factor, beta receptor II cDNA driven by the tetracycline operator (tetO). The Tgfbr2 cDNA contains a truncation mutation, resulting in a complete deletion of the transmembrane and intracellular domains. (J:114572)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
