A loxP site was inserted upstream of exon 1 and an FRT site flanked neomycin resistance gene cassette and a second loxP site were inserted into intron 1. The neo cassette was removed through subsequent FLP-mediated recombination, leaving a conditional-ready allele with a floxed exon 1. (J:239911)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count