Exon 2 was flanked by loxP sites, and two frt- or F3-flanked positive selection markers that were used in order to increase co-recombination frequency of both loxP sites were removed by Flp-mediated recombination. (J:229864)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count