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A loxP site flanked beta-geo (lacZ (beta-galactosidase) and neomycin resistance gene fusion) cassette was inserted into the intron upstream of exon P. A further loxP site was inserted into the intron downstream of exon P+2. These P exons encode ATP-binding P loops. Subsequent cre-mediated recombination created this conditional-ready allele, with the beta-geo cassette removed and the targeted exons P, P+1 and P+2, remaining floxed. (J:239635)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
