A loxP site was inserted upstream of exon 1 and a further loxP site and an FRT site flanked neomycin resistance gene cassette into intron 1. The neo cassette was removed through subsequent flp-mediated recombination, leaving a conditional-ready allele with a floxed exon 1. (J:239656)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count