An internal ribosome entry site (IRES)-cre was fused to exon 1, disrupting the mouse Pou4f2 gene. A neomcyin cassette, in reverse transcriptional orientation, was placed downstream. (J:239733)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count