Fgfr1^tm10.1Sor

Exon 9 was replaced with a modified one in which nucleotide substitutions result in silent mutations and the amino acid substitution of alanine for leucine at position 423 (L423A). Exon 10 was replaced with one in which nucleotide substitutions result in a silent mutation and the amino acid substitution of alanine for valine at position 429 (V429A) and phenylalanine for tyrosine at position 463 (Y463F). Exon 18 was replaced with one in which nucleotide substitutions result in the amino acid substitution of phenylalanine for tyrosine at positions 766 and 776 (Y766F, Y776F). Cre-mediated recombination removed the floxed neomycin resistance cassette inserted in intron 9. (J:226497)