This transgene consists of a 4.3-kb portion of human SHBG that comprises all eight exons plus 0.9 kb 5' of the translation initiation codon in exon 1 and 0.5 kb 3' from the polyadenylation sequence in exon 8. Three lines (4-a, 4-b, and 4-c) were generated. The transgene integrated as head to tail multimers with an estimated copy number of 11. (J:239368)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(CBA x C57BL/6)F2
--
Insertion
--
1
--
8

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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