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This transgene consists of the mouse mammary tumor virus long terminal repeat (MMTV LTR), 5'-untranslated region from the HaSv, sequences encoding oncogenically mutated (glycine to valine at codon 12) human Kirsten (Ki)-rasB, and SV40 polyadenylation sequence. Highest level of transgene expression is in mammary tissue and no expression is seen in the kidney, liver or spleen. (J:77272)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
