A MAPT-lacZ (tau-LacZ) fusion reporter followed by a floxed neomycin resistance cassette replaced the coding sequence of exon 1. Cre-mediated recombination removed the selection cassette. Immunofluorescence confirmed the absence of portein expression in spinal cord-derived neurospheres. (J:233502)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S4/SvJae
Targeted
Insertion, Intragenic deletion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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