Plasmids encoding a signal guide RNA designed to introduce an E2A peptide cleavage site-cre/ERT2 into the last exon of the Pax9 gene (immediately before the stop codon) and the cas9 nuclease were introduced into the cytoplasm B6D2F1-derived fertilized eggs with well-recognized pronuclei. (J:236319)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count