Plasmids encoding a signal guide RNA designed to introduce an E2A peptide cleavage site-cre/ERT2 into the last exon of the Pax9 gene (immediately before the stop codon) and the cas9 nuclease were introduced into the cytoplasm B6D2F1-derived fertilized eggs with well-recognized pronuclei. (J:236319)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x DBA)F1
Endonuclease-mediated
Insertion
--
1
3
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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