A loxP-flanked PGK-neomycin selection cassette replaced exons 1-4 of the gene. Immunoblotting analysis showed that protein expression was absent in multiple tissues of homozygous mutant neonate mice, while the protein was highly expressed in the brain, spleen and intestine in control neonate mice. (J:238623)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129
Targeted
Insertion, Intragenic deletion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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