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EN
A construct comprising a CAG promotor, the ascidian Ciona intestinalis AOX (alternative oxidase) gene, a beta globin intron and a polyA site, plus an FLP site flanked neomycin resistance gene cassette were inserted into the locus. The neo cassette was removed through flp-mediated recombination. This creates an allele ubiquitously expressing an oxidase gene of a type not found in mammals. (J:238705)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
