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The targeting vector contains a loxP-flanked PGKneo cassette upstream of Biotin-3xFLAG (BioFL) sequence (encoding a biotin recognition motif and 3 copies of the FLAG epitope) inserted at the C-terminus of the Sp7 gene. Cre-mediated recombination removed the upstream floxed neo cassette. Western blotting detects the modified allele at slightly reduced levels as compared to wild-type. Temporal and spatial distributions is equivalent to the endogenous Sp7 gene expression. (J:235520)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
