This transgene shows skin-specific expression of mouse Dkk4 under KRT14 promoter control. Sharply elevated expression in the back skin of transgenic mice from E14.5 was detectable by Q-PCR assays, and Western blotting confirmed the increased expression of Dkk4 protein in the soluble fraction of E16.5 transgenic skin extract. No line information was given. (J:238689)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count