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An NF-kappaB responsive minigene containing three tandem HIV-derived kappaB binding element repeats was placed proximal to a minimal promoter derived from SV40. Upon NF-kappaB binding, this construct drives expression of beta-galactosidase that was modified to include an SV40 T-antigen-derived nuclear localization sequence. 10 founder lines were generated, and three founder lines (17814, 17815, and 17819) were kept and studied further. (J:79207)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
