The entire mouse Mpz gene (including 6 kb of promoter sequences, all exons and introns, and the natural polyadenylation site) was used as the transgene. A myc tag was inserted at the end of the coding region. Twelve lines were generated, and line 140.12 was kept for further analysis. (J:171510)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count