The targeting vector was designed with (from 5' to 3') a loxP-flanked STOP cassette (neo with 3x polyA), jagged 1 (JAG1) human cDNA, and an internal ribosome entry site (IRES) fused to a luciferase sequence. This targeting vector was inserted between exons 1 and 2 of the Gt(ROSA)26Sor. (J:238768)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count