Log In|Sign Up
EN
Nonchemically modified deoxyribonucleotides were used to introduce the (5-ATGCAGAAAATCTTAGAGTAGGCGATCTGGTAAGTCAACA-3) mutation into a mouse ES cell line. This alteration is a substitution of 3 nucleotides (TCC to AAG) at position 185, resulting in an early STOP codon at aa 24 of the encoded protein. (J:237116)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
