TALENs were designed to target exon 1 of the gene. Western blot analysis on mouse fibroblast lysates derived from homozygous mice showed that no detectable protein is expressed from this allele. (J:233671)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count