Triple mutants were created with exons 2, 14 and 18 targeted. Exon 2 guide RNA target sequence: AGCATACGTCTGTGGATGGC; exon 14 target sequence: CGTATATTCTGGCGGTAGCA; exon 18 target sequence: AACGACATGCTGAGGGAGAT. Seven triple mutants were identified through qPCR. The specific mutations in these strains are not reported. The pound (#) symbol is used for the pool of all seven founders. (J:238422)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x C3H)F1
Endonuclease-mediated
Not Specified
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Comparison
Al agent
Tutorials
Back to top