A loxP site was introduced to intron 1 and a FRT-flanked neomycin cassette followed by a loxP site was placed in intron 2. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exon 2 floxed. (J:238330)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count