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The targeting construct was generated by insertion of a FRT-NEO-FRT-IRES-CRE cassette between the stop codon and the polyA site of the gene. Homologous recomination in ES cells generated correctly targetted mice. Crossing resulting mice with FlpO deleter mice removed the selection cassette. (J:238329)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
