Mice bearing this transgene express human teratocarcinoma-derived growth factor 1 (TDGF1; also called Cripto-1 or CR-1) under control of the promoter of the whey acidic protein gene (Wap). The transgene contains the Wap promoter followed by the coding sequence of human TDGF1 cDNA, flanked by 220 bp of 5'- and 110 bp of 3'- untranslated region (UTR) DNA, and the bovine growth hormone polyadenylation signal. (J:99942)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
--
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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