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Cre-mediated recombination has deleted a DNA segment extending from 335 bp upstream of exon 2, which contains the entire coding sequence, to a site 550 bp downstream of the stop codon within the exon, leaving a single loxP site. The remaining 66 bp of exon 2 were deleted in the original targeted allele, Grem1tm1Ecan (J:126375)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
