The targeting vector contains a loxP-flanked FLAG-myc-STOP cassette upstream of an EGFP sequence, all inserted in-frame into the endogenous stop codon. Prior to Cre recombinase exposure, expression of FLAG/myc-tagged RAI1 is observed in a pattern consistent with the endogenous gene, and no EGFP expression is reported. (J:237687)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count