This allele from project Zfp92-8178J-M8966 was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences GTGCTCTAAGATTCATGCAG, GTTTTCATTTCGGATTACCC, TTATCTTACCTATAACTTGT and GTGCGGAAAATGGGTCTGAC, which resulted in a 518 bp deletion beginning at Chromosome X positive strand position 73,419,955 bp, TTTCCACTGCATGAATCTTA, and ending after ATAACAACCTGTCAGACCCAT at 73,420,472 bp (GRCm38/mm10). This mutation deletes exon 4 and 391 bp of flanking intronic sequence including the splice acceptor and donor, and is predicted to cause a change of amino acid sequence after residue 11 and early truncation 37 amino acids later. (J:188991)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count