This transgene consists of a fos-lacZ fusion protein containing 315 N-terminal amino acids from the mouse c-fos and 1015 C-terminal amino acids from beta-galactosidase. The construct lacks the C-terminal amino acid sequences that function as a negative regulator of c-fos expression. Three lines were established, however the pound symbol (#) is used because lines are not specified. (J:237479)
Basic Information
(C57BL/6 x C3H)F1 x (C57BL/6 x DBA/2)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count