Flp excision of the parental Snap29tm1a(EUCOMM)Wtsi allele removes the lacZ/neo cassette leaving behind a loxP-flanked critical exon 2. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:236759)