The targeting vector containing a loxP site, PGK-puromycin-pA cassette (in reverse transcriptional orientation), 4x SV40-pA STOP, loxP, and FLAG-human ATF4-WPRE-BGH-pA cassette sequence is introduced to the Gt(ROSA)26Sor gene via a FLP recombinase-mediated cassette exchange method. (J:237331)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count