The targeting vector is designed to insert a loxP-flanked neomycin resistance (neo) cassette upstream of exon 5 and a third loxP site downstream of exon 9. Cre-mediated recombination removed the floxed neo cassette. (J:239534)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count