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The transgene contains a tetracycline responsive element, comprising seven tandem copies of the tetracycline operator (tetO), driving bidirectional expression of cDNAs encoding human MYC (melanocytomatosis oncogene; also called c-myc)(exons 2-3) and cytosolic chicken ovalbumin (OVAL; also called SERPINB14) from oppositely-oriented human cytomegalovirus (CMV) minimal promoters. (J:186226)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
