CRISPR/Cas9 system was used to generate a 91,795 bp deletion using 5 gRNA cut at Chr10:123,196,931 upstream of exon 1 and a 3 gRNA cut at Chr10:123,105,136, downstream of the last exon, exon 22. The sequence at the fusion point is: gccgccgcctccgctaTcGGatcgtatcaagtgacat (capital letters: different from expected fusion product). (J:306500)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6J
Endonuclease-mediated
Intragenic deletion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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