Itk^m1Btlr

ENU-induced A to G transition at base pair 46,338,217 (GRCm38) on chromosome 11, or base pair 51,299 in the GenBank genomic region NC_000077. The mutation corresponds to residue 1,240 in the mRNA sequence NM_001281965, within 12 of 17 exons. The mutation results in a phenylalanine to leucine substitution at position 379 (F379L) in the protein (isoform 1). (J:236673)