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The full-length murine Arl3 with the Q71L dominant active mutation is under the control of a 4.4-kb rhodopsin promoter. A tandem C-terminally hemagglutinin (HA) and FLAG fusion tags were added. The rhodopsin promoter drives the expression of the gene as early as postnatal day 4 in rod photoreceptor cells of the retina. Immunoblotting indicates 2.5-fold overexpression of the mutant over endogenous levels. The pound symbol (#) is used when line is not specified and/or lines are pooled. (J:235882)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
