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The trangene cassette was generated by inserting the reporter cassette downstream of the translation initiation sequence in BAC RP24-164C18. The mouse promoter drives molecular layer interneuron-specific expression of the mammalian codon-optimized Chlamydomonas reinhardtii-derived channel rhodopsin-2 that was modified to harbor a gain-of-function H134R substitution (hChR2-H134R) fused in-frame with a yellow fluorescent protein (YFP) and followed by a bovin growth hormon 3'UTR. Line 3 was generated. (J:236224)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
