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The targeting vector was designed to insert an eGFPCreERT2 (GCE) fusion protein coding sequence and loxp-flanked neo selection cassette into just after the stop codon of the last exon of Olfm4 gene, making use of the endogenous poly A signal. Positive clones were injected into blastocysts to establish the mouse line. The neomycin selection cassette was excised in vivo by crossing the mice with the PGK-Cre mouse strain. (J:232454)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
