A PGK-neo cassette flanked by two loxP sites was inserted in the intron preceding exon 2 and another loxP site was inserted following exon 9. Cre-mediated recombination removed the selection cassette and left exons 2 through 9 floxed. (J:227564)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count