An IRES-cre/ERT2 cassette followed by an rox-flanked neo selection cassette was inserted into the 3' UTR by homologous recombination. Mice were crossed to Dre-expressing mice to delete the rox-flanked neo cassette. (J:234789)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count