The targeting construct contains a tetO (tetracycline response element; TRE)-loxP-Stop-loxP-Optopatch3-CAG-tTA (tetracycline-controlled transactivator). Optopatch3 is a bicistronic construct that coexpresses QuasAr3-mCitrine (an enhanced archaerhodopsin-3 (Arch)-based voltage indicator) and CheRiff (a sensitive blue-shifted optogenetic actuator) (J:101977)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(129S6/SvEvTac x C57BL/6NCrl)F1
Targeted
Insertion
--
--
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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