A retrotransposon consisting of a small interspersed element (SINE) spontaneously inserted into the 3'UTR. This insertion provides a new polyadenylation signal and terminates the mRNA prematurely. Western blot analysis confirmed increased protein expression in bone marrow-derived macrophage lysates. (J:226052)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count