A single loxP site was introduced between exons 7 and 8 and a neomycin selection cassette flanked by frt sites with a single loxP site was inserted between exons 3 and 4. Flp-mediated recombination removed the neomycin cassette leaving exons 4-7 flanked by loxP sites. (J:226703)
Basic Information
129S1/Sv-Oca2+ Tyr+ Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count