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EN
This transgene contains the promoter of the glial fibrillary acidic protein (Gfap) gene directing expression of a full-length human phosphatase and tensin homolog (PTEN) cDNA that has been modified to substitute an alanine codon for that encoding each of the five amino acids in the C-terminal tail that are phosphorylated by casein kinase 2 (CK2): serine 370, serine 380, threonine 382, threonine 383, and serine 385 (S370A/S380A/T382A/T383A/S385A; PTEN QMA). (J:82809, J:234161, J:234163)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
