An FRT-flanked neomycin resistance cassette was inserted downstream of a floxed exon 7. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exon 7. Western blot analysis of testis protein extracts confirmed the absence of full-length protein in homozygous mutant mice. (J:228765)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count